Hepatitis B Vaccine. When is it give? Why is it given? How is it given? Is it safe?

Find out the answers to these questions, and more!

According to the CDC recommended vaccine schedule, infants are given the Hepatitis B vaccine in a three-dose series at birth, 1-2 months, and 6-18 months.

But, if you read the footnotes, when given in combination vaccines there can be 4 doses administered instead of just the recommended 3!!!!

"Routine Series:

• A complete series is 3 doses at 0, 1–2, and 6–18

months. (Monovalent HepB vaccine should be

used for doses given before age 6 weeks.)

• Infants who did not receive a birth dose should

begin the series as soon as feasible (see Figure 2).

• Administration of 4 doses is permitted when a

combination vaccine containing HepB is used after

the birth dose.

• Minimum age for the final (3rd or 4th) dose: 24


• Minimum Intervals: Dose 1 to Dose 2: 4 weeks /

Dose 2 to Dose 3: 8 weeks / Dose 1 to Dose 3: 16

weeks. (When 4 doses are given, substitute “Dose

4” for “Dose 3” in these calculations.)"

Acute Disseminated Encephalomyelitis following Vaccination against Hepatitis B in a Child: A Case Report and Literature Review

Hepatitis B vaccination of male neonates and autism diagnosis, NHIS 1997-2002

The persistence of anti-HBs antibody and anamnestic response 20 years after primary vaccination with recombinant hepatitis B vaccine at infancy.

Adverse events associated with the hepatitis B vaccine in U.S. children less than six years of age, 1993, and 1994.

A one-year follow-up of chronic arthritis following rubella and hepatitis B vaccination based upon analysis of the Vaccine Adverse Events Reporting System (VAERS) database.

"After reviewing the literature, we observed that complications seen after Hepatitis B vaccination are sudden infant death syndrome, multiple sclerosis, chronic fatigue syndrome, idiopathic thrombocytopenic purpura, vasculitis optic neuritis, anaphylaxis, systemic lupus erythematosus, lichen planus, and neuro-muscular disorder. "

Hepatitis B vaccination and associated oral manifestations: a non-systematic review of literature and case reports


Hepatitis B vaccine induces apoptotic death in Hepa1–6 cells

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